Genomics Data Management – Researcher position

About the University

The University of Luxembourg aspires to be one of Europe’s most highly regarded universities with a distinctly international and interdisciplinary character. It fosters the cross-fertilisation of research and teaching, is relevant to its country, is known worldwide for its research and teaching in targeted areas, and is establishing itself as an innovative model for contemporary European Higher Education. It`s core asset is its well-connected world-class academic staff which will attract the most motivated, talented and creative students and young researchers who will learn to enjoy taking up challenges and develop into visionary thinkers able to shape society.

Within the University, the Luxembourg Centre for Systems Biomedicine (LCSB) is a highly interdisciplinary research centre (IC), integrating experimental biology and computational biology approaches in order to develop the foundation of a future predictive, preventive and personalized medicine.

The Bioinformatics Core at LCSB is looking for a researcher for a position in Genomics Data Management in the Bioinformatics Core of the LCSB. The LCSB received a mandate of an international group of geneticists organized within the International League Against Epilepsy (ILAE, https://www.ilae.org rel="noopener noreferrer" target="_blank">https://www.ilae.org) to build the infrastructure for a task force on sequencing data sharing and analytics. The LCSB is already hosting the complete ILAE genotype data collected world-wide. Within this research project, in addition we will start collecting and analysing the largest collection of whole exome sequencing (WES) data in the field of genetic epilepsy. The goal is to collect all publicly available epilepsy WES data from data sources like dbGAP like the data from the Epi25 consortium and to combine this data with already existing WES collections at LCSB from large cohort studies like CoGIE and EpiPGX.

Your Role

• To organize sequencing data acquisition and transfer to the Luxembourg Centre of Systems Biomedicine (LCSB)


• Scientific contact point for all researchers, national and international stakeholders providing and requesting data


• Pre-clinical and clinical data curation, harmonization, integration and analysis.


• Retrieval, curation and analysis of project specific data from public genomic data repositories and literature.


• Support data driven repurposing and rational selection of drug candidates.


• Management of ethical and legal issues including approval of broad data sharing consent


• Further develop and collect data sharing and research agreements with scientists and industrial partners


• Overseeing data formats and transfer management


• Customizing, programming, and administering genomic data storage and data access management in a genomic Laboratory Information Management System (LIMS)


• Deployment and maintenance of a data and computing platform.

Your Profile

• A Master or PhD in Computational Biology, Bioinformatics, Computer Science or related fields, with a strong interest in data and project management


• Working knowledge of a modern programming languages used in scientific computing (Python, R)


• Strong experience working and programming in a Unix environment and HPC infrastructure


• Basic knowledge in human genetics and next generation sequencing


• Excellent communication skills and the ability to articulate clearly the scientific and technical needs and to work within an interdisciplinary setting, communicating with other internal/external partners.


• Prior experience dealing with pre-clinical, clinical, genetic and genomic data integration, in general is considered as an advantage.


• Demonstrated ability to work independently.


• Knowledge of best practices for with organizing, replicating, and backing up high-volume data.


• Strong interpersonal and communication skills with a diversity of technical and non-technical collaborators, clinicians and legal teams

We offer

• A fully funded position with a competitive salary (contract subject to national public social security scheme including health care).


• Participate in the building of state-of-the-art translational medicine platform.


• An opportunity to join the fast-growing Bioinformatics Core Facility group headed by Prof. Dr. Reinhard Schneider in LCSB, University of Luxembourg.

In Short

• Contract Type: Fixed Term Contract 24 Month


• Work Hours: Full Time 40.0 Hours per Week


• Location: Belval


• Job Reference: UOL03723

Further Information

Applications (in English) should contain the following documents:

• A detailed curriculum vitae


• Cover letter mentioning the reference number


• List of publications/software projects


• Description of past experience and future interests


• Name and addresses of three referees

Early application is highly encouraged, as the applications will be processed upon reception. Please apply ONLINE formally through the HR system. Applications by email will not be considered.

The University of Luxembourg embraces inclusion and diversity as key values. We are fully committed to removing any discriminatory barrier related to gender, and not only, in recruitment and career progression of our staff.

Here’s what awaits you at the University

• Multilingual and international character. Modern institution with a personal atmosphere. Staff coming from 90 countries. Member of the “University of the Greater Region” (UniGR). 


• 
  A modern and dynamic university. High-quality equipment. WiFi on campus. Close ties to the business world and to the Luxembourg labour market. A unique urban site with excellent infrastructure.


• 
  A partner for society and industry. Cooperation with European institutions, innovative companies, the Financial Centre and with numerous non-academic partners such as ministries, local governments, associations, NGOs …


• https://urldefense.proofpoint.com/v2/url?u=https-3A__wwwen.uni.lu_univer... rel="noopener noreferrer" target="_blank">Find out more about the University


• https://urldefense.proofpoint.com/v2/url?u=https-3A__wwwen.uni.lu_contac... rel="noopener noreferrer" target="_blank">Addresses, maps & routes to the various sites of the University

Further information

For questions, please contact Dr. Roland Krause (mailto:roland.krause@uni.lu rel="noopener noreferrer" target="_blank">roland.krause@uni.lu) or Dr. Patrick May (mailto:patrick.may@uni.lu rel="noopener noreferrer" target="_blank">patrick.may@uni.lu).